Dr. Sam Glover – Analytical/Physical Seminar
BME Seminar Series: Dr. Damir Janigro, Flocel Inc.
“Blood-brain barrier in health and diesase”
The blood-brain barrier (BBB) serves to protect the central nervous system (CNS) from damage by exogenous molecules. In doing so, it also can prevent some drugs from reaching their sites of action. A variety of CNS disorders contribute to BBB disruption, and detection of this “opening” can be used for both diagnostic purposes and for determining time periods when drugs can more easily enter the CNS. While expensive and time-consuming imaging techniques are currently used for this purpose, we have devised a method for detecting plasma levels of a blood biomarker of BBB disruption. The relevance of these findings in translational neurosciences will be discussed.
DR. DAMIR JANIGRO, PhD, FAES is the CSO and founder of Flocel Inc. a Professor at CWRU, a member of the World Neurobiology Commission of ILAE, and associate editor for Epilepsia, PLOS among others. He has over 30 years of experience and has received continuous support from the NIH since 1996. He is the inventor of the dynamic in vitro model of the BBB that constituted one of the founding blocks of Flocel’s technology. He discovered S100B as a marker of BBB function and has for many years collaborated with top notch hospitals in the US and Europe to broaden the scope and use of this technology. He recently patented the use of S100B as marker of hemorrhagic transformation in stroke victims undergoing intra-arterial therapies. With his former student, Dr. Nicola Marchi, he received the Morris-Coole award in 2008. He has served on several NIH panels, and has been part of three FDA applications. He served as Chairman for study sections for the American Heart Association and the Department of Defense. He has been associated with neurosurgeons and neurointensivists since his post-doctoral years at the University of Washington (1994-1999). He has published over 150 papers.
Colloquium – Rafael Lang (Purdue) Dark Matter and How To Go About It
This talk will give an overview of astrophysical and cosmological evidence for Dark Matter. While this will make it clear that Dark Matter does exist, it remains entirely unknown what it is made of. Many well-motivated models predict Dark Matter particles with masses between
10 and 10,000 proton masses. Various techniques exist to tackle the search for such particles. This talk will present XENON1T, the most sensitive experiment ever built to search for Dark Matter scattering off a laboratory target. Given availability, new results from XENON1T will be presented. An outlook will be given over a variety of searches that are possible with XENON1T, from unconventional forms of Dark Matter to neutrinos from the Sun and supernova explosions anywhere in the Milky Way.
CAR Seminar Series: Bharat Hegde, graduate student, Department of Mechanical and Aerospace Engineering / Ghulam Murtaza, visiting scholar, Mohammad Ali Jinnah University
Presenters: Bharat Hegde, graduate student, Department of Mechanical and Aerospace Engineering / Ghulam Murtaza, visiting scholar, Mohammad Ali Jinnah University
Topics: “Look-ahead energy management scheme for on-highway commercial vehicles” (Hedge) / “Modeling and control of Atkinson cycle engine” (Murtaza)
Join faculty, staff, visiting scholars and graduate students to learn about various automotive engineering topics during this weekly seminar series in spring semester 2017. Held in the classroom/room 198 at the Center for Automotive Research. Follow the conversation online: #CARSeminarSeries.
Denman Forum Overview
The Denman Undergraduate Research Forum, now in its 22nd year, is coordinated by the Undergraduate Research Office and generously supported by Mr. and Mrs. Denman, the Office of Research, the Office of Undergraduate Education, and corporate and private donors. The Denman Forum provides an opportunity for undergraduate students to showcase their research, scholarship, and creative activities to the OSU community and beyond.
About Mr. and Mrs. Denman
Mr. and Mrs. Denman are long-time members of the Ohio State University community and proud supporters of the Denman Undergraduate Research Forum, since its inception. In addition, they have established the Richard J. and Martha D. Denman Undergraduate Research Forum Endowment Fund. They also have established a Professorship for Clinical Research in Epilepsy and The Richard J. and Martha D. Denman Fund for Basic and Clinical Research in Epilepsy in Memory and Honor of their son, Richard (Rik) J. Denman, Jr. Both Mr. and Mrs. Denman are Inaugural Members of the Oval Society, established in 2010 and lifetime members of the President’s Club and the Ohio State Alumni Association. Mr. Denman served as an Ohio State University Foundation Board Charter Member Director (1985-2003) and is now an Emeritus member and Lifetime Director of the Board. He is a member of Medicine’s Order of Hippocrates, as well. In 1996, the University presented him with a Distinguished Service Award.
BME Seminar Series: Dr. Giuliano Scarcelli, University of Maryland
More details coming soon.
Dr. Richard Vachet – Biochemistry Seminar Series
Lowrie Lecture I: Eric Kaler
Registration is limited to the first 40 registrants for each session.
Direct questions about presentations to Brenner.email@example.com.
Seminar: New Solution Paradigms for Uncertainty Forecasting in High-Dimensional Nonlinear Stochastic Systems
In this talk, we will look at a snapshot of the new Laboratory for Autonomy in Data Driven and Complex Systems (LADDCS) at the Aerospace Research Center (ARC). LADDCS focuses on theoretical and computational research in uncertainty characterization, forecasting and fusion, as well as control of uncertain (better known as stochastic) systems. Challenges associated with the Fokker-Planck equation (FPE), a holy grail problem in stochastic dynamics will be discussed. Two fundamentally distinct solution paradigms will be presented – i.) tensor-based discretization, and, ii.) adaptive particle discretization in the framework of Monte Carlo methods. The key objective of both classes of methods is to accurately capture non-Gaussianity while alleviating the curse of dimensionality. We will present our results in a wide variety of fields, including weather-forecasting, space-situational awareness and the modeling of polymeric fluids.
About the Speaker
Dr. Mrinal Kumar received a Ph.D. in 2009 from Texas A&M University and a Bachelor’s degree in 2004 from the Indian Institute of Technology, Kanpur, both in aerospace engineering. Before joining OSU in Fall 2016 as an Associate Professor in the MAE department, he was an Assistant Professor in the same department at the University of Florida. At OSU, Dr. Kumar founded the Laboratory for Autonomy in Data-Driven and Complex Systems (LADDCS), which is home to research in nonlinear stochastic dynamical systems, Fokker‐Planck equations, Markov‐chain Monte Carlo methods, stochastic optimization and chance-constrained optimization and control. He received the Best Paper of Conference Award at the 2006 Astrodynamics Specialist Conference, the 2007 AIAA Open Topic Graduate Research Award, and more recently, the NSF CAREER Award in 2013 and the AFOSR Young Investigator Award in 2015.