Calendar

Oct
2
Mon
Seminar: Eric Ruggiero @ E100 Scott Lab
Oct 2 @ 11:00 am – 12:00 pm

Affiliation: GE Aviation, Cincinnati, OH

Hosted by: Professor Marcelo Dapino

Student Seminar – Yongze Yu @ 1005 Smith Lab
Oct 2 @ 4:10 pm – 5:10 pm

Speaker: Yongze Yu

Title: Electron Transfer Kinetics of a Series of Bilayer Triphenylamine-Oligothiophene-Perylenemonoimide Sensitizers for Dye-Sensitized NiO

Advisor: Dr. Wu

Oct
3
Tue
CAR Seminar Series: Tong Zhao @ 198 Center for Automotive Research
Oct 3 @ 4:30 pm – 5:30 pm

Host: Giorgio Rizzoni

Speaker: Tong Zhao

Title: Benchmarking ECMS Algorithm with Dynamic Programming

Oct
5
Thu
BME Seminar Series: Dr. Yizhou Dong @ 245 Bevis Hall
Oct 5 @ 10:00 am – 11:00 am

Speaker: Dr. Yizhou Dong

Affiliation: The Ohio State University

Title: Development of nanomaterials for mRNA therapeutics and genome editing

 

Abstract:

Messenger RNA (mRNA) therapeutics have shown great promise for purpose of expressing functional proteins. However, the efficient and safe delivery of mRNA remains a key challenge for the clinical application of mRNA based therapeutics. Lipid and lipid-like nanoparticles possess the potential for mRNA delivery. Based on our previous experiences, we have designed and synthesized N1,N3,N5-tris(2-aminoethyl)benzene-1,3,5-tricarboxamide (TT). We applied an orthogonal experimental design to investigate the impacts of formulation components on delivery efficiency. TT3 LLNs, a lead material fully recovered the level of human factor IX (hFIX) to normal physiological values in FIX-knockout mice. In addition, we demonstrated that TT3 LLNs were capable of effectively delivering Cas9 mRNA and guide RNA to the mouse liver for genome editing.

 

Bio:

Dr. Dong received his Ph.D. degree in pharmaceutical sciences from the University of North Carolina at Chapel Hill (UNC-CH) in 2009 under the supervision of Professor K.-H. Lee. He was a postdoctoral fellow from 2010-2014 in Children’s Hospital Boston at Harvard Medical School and also in the David H. Koch Institute for Integrative Cancer Research at MIT in the laboratory of Professors Robert Langer and Daniel Anderson. He also holds B.S. in pharmaceutical sciences from Peking University, Health Science Center (2002) and M.S. in organic chemistry from Shanghai Institute of Organic Chemistry (2005). He joined the Division of Pharmaceutics and Pharmaceutical Chemistry at The Ohio State University as Assistant Professor in 2014.

Biochemistry Seminar – Dr. Natalia Tretyakova @ 111 Parks Hall
Oct 5 @ 11:30 am – 12:30 pm

Title: TBA

Affiliation: University of Minnesota

Hosted by: Dr. Musier-Forsyth

CBE Seminar: Anna Balazs @ 130 Koffolt Lab
Oct 5 @ 11:30 am – 12:30 pm

Speaker: Anna Balazs, Distinguished Professor, Chemical and Petroleum Engineering

Affiliation: University of Pittsburg

Details TBD

Oct
6
Fri
Fall 2017 EAB @ Transportation Research Center, Inc.
Oct 6 @ 9:00 am – 3:00 pm

An exciting day highlighting autonomous and connected vehicle research, motorsports updates, TRC tours and activities as well as remarks from David Williams, Dean, College of Engineering and Giorgio Rizzoni, Director, Center for Automotive Research is being planned.

Questions may be directed to Jennifer Nash Humphrey at 614-292-5990 or car@osu.edu

Oct
9
Mon
Construction Career Expo – Fall 2017 @ Ohio Farm Bureau 4H Center
Oct 9 @ 10:00 am – 2:00 pm

https://students.cfaes.ohio-state.edu/careers/career-expos

Analytical/Physical Seminar – Dr. Thorsten Bernhardt @ 2004 Evans Laboratory
Oct 9 @ 4:10 pm – 5:10 pm

Title: TBA

Affiliation: Ulm University

Hosted by: Dr. Zhong

Oct
10
Tue
Graduation Services Seminar @ 130 Koffolt Lab
Oct 10 @ 11:30 am – 12:30 pm

Speaker: Tim Watson, Director of Graduation Services

For graduate students approaching graduation: Come and learn about graduation requirements from the Graduate School.