Calendar

Sep
26
Tue
CAR Seminar Series: Avinash Vallur @ 198 Center for Automotive Research
Sep 26 @ 4:30 pm – 5:30 pm

Host: Giorgio Rizzoni

Speaker: Avinash Vallur

Title: Simulation of Look-Ahead Based Energy Management Strategy using Traffic In Loop Framework

Sep
28
Thu
BME Seminar Series: Dr. Matthew Becker @ 245 Bevis Hall
Sep 28 @ 10:00 am – 11:00 am

Speaker: Dr. Matthew Becker, Associate Dean for Research; W. Gerald Austen Endowed Chair in Polymer Science and Polymer Engineering

Affiliation: University of Akron

Title: Building bone with polymers – How new materials and additive manufacturing are changing medicine

 

Abstract:

Recent synthetic advances have enabled the synthesis of polymers designed to elicit specific cellular functions and to direct cell-cell interactions.  Motivated by traumatic injuries experienced by warfighters, we are developing novel materials and devices designed to repair segmental bone defect and achieve limb salvage.  Biomimetic approaches based on polymers derivatized with adhesive receptor-binding peptides glycoproteins and tethered growth factors have been reported to enhance interactions at the biotic-synthetic interface.  Further advances in both synthetic methodology and scaffold fabrication are needed to drive these efforts forward.  This presentation will describe the use of several translationally relevant chemistries and functionalization strategies that are impacting the practice of medicine and how physicians are planning for future therapies that were not possible previously.

 

Bio:

Matthew L. Becker is the W. Gerald Austen Endowed Chair of Polymer Science and Polymer Engineering and The Associate Dean for Research in the College of Polymer Science and Polymer Engineering at The University of Akron.  His multidisciplinary research team is focused on developing bioactive polymers for regenerative medicine and addressing unmet medical needs at the interface of chemistry, material science and medicine. He is the founder of three start-up companies.  He earned  a PhD in organic chemistry at Washington University in St. Louis as an NIH Chemistry Biology Interface Training Fellow. In 2003, Dr Becker moved to the Polymers Division of the National Institute of Standards and Technology for a NRC Postdoctoral Fellowship. He joined the permanent staff as a project leader in 2005 before moving to The University of Akron in 2009.   Professor Becker was awarded the ACS Publications Macromolecules-Biomacromolecules Young Investigator Award in 2015 and is a fellow of the ACS PMSE Division and the Royal Society of Chemistry.

Oct
2
Mon
Seminar: Eric Ruggiero @ E100 Scott Lab
Oct 2 @ 11:00 am – 12:00 pm

Affiliation: GE Aviation, Cincinnati, OH

Hosted by: Professor Marcelo Dapino

Student Seminar – Yongze Yu @ 1005 Smith Lab
Oct 2 @ 4:10 pm – 5:10 pm

Speaker: Yongze Yu

Title: Electron Transfer Kinetics of a Series of Bilayer Triphenylamine-Oligothiophene-Perylenemonoimide Sensitizers for Dye-Sensitized NiO

Advisor: Dr. Wu

Oct
3
Tue
CAR Seminar Series: Tong Zhao @ 198 Center for Automotive Research
Oct 3 @ 4:30 pm – 5:30 pm

Host: Giorgio Rizzoni

Speaker: Tong Zhao

Title: Benchmarking ECMS Algorithm with Dynamic Programming

Oct
5
Thu
BME Seminar Series: Dr. Yizhou Dong @ 245 Bevis Hall
Oct 5 @ 10:00 am – 11:00 am

Speaker: Dr. Yizhou Dong

Affiliation: The Ohio State University

Title: Development of nanomaterials for mRNA therapeutics and genome editing

 

Abstract:

Messenger RNA (mRNA) therapeutics have shown great promise for purpose of expressing functional proteins. However, the efficient and safe delivery of mRNA remains a key challenge for the clinical application of mRNA based therapeutics. Lipid and lipid-like nanoparticles possess the potential for mRNA delivery. Based on our previous experiences, we have designed and synthesized N1,N3,N5-tris(2-aminoethyl)benzene-1,3,5-tricarboxamide (TT). We applied an orthogonal experimental design to investigate the impacts of formulation components on delivery efficiency. TT3 LLNs, a lead material fully recovered the level of human factor IX (hFIX) to normal physiological values in FIX-knockout mice. In addition, we demonstrated that TT3 LLNs were capable of effectively delivering Cas9 mRNA and guide RNA to the mouse liver for genome editing.

 

Bio:

Dr. Dong received his Ph.D. degree in pharmaceutical sciences from the University of North Carolina at Chapel Hill (UNC-CH) in 2009 under the supervision of Professor K.-H. Lee. He was a postdoctoral fellow from 2010-2014 in Children’s Hospital Boston at Harvard Medical School and also in the David H. Koch Institute for Integrative Cancer Research at MIT in the laboratory of Professors Robert Langer and Daniel Anderson. He also holds B.S. in pharmaceutical sciences from Peking University, Health Science Center (2002) and M.S. in organic chemistry from Shanghai Institute of Organic Chemistry (2005). He joined the Division of Pharmaceutics and Pharmaceutical Chemistry at The Ohio State University as Assistant Professor in 2014.

Biochemistry Seminar – Dr. Natalia Tretyakova @ 111 Parks Hall
Oct 5 @ 11:30 am – 12:30 pm

Title: TBA

Affiliation: University of Minnesota

Hosted by: Dr. Musier-Forsyth

CBE Seminar: Anna Balazs @ 130 Koffolt Lab
Oct 5 @ 11:30 am – 12:30 pm

Speaker: Anna Balazs, Distinguished Professor, Chemical and Petroleum Engineering

Affiliation: University of Pittsburg

Details TBD

Oct
9
Mon
Analytical/Physical Seminar – Dr. Thorsten Bernhardt @ 2004 Evans Laboratory
Oct 9 @ 4:10 pm – 5:10 pm

Title: TBA

Affiliation: Ulm University

Hosted by: Dr. Zhong

Oct
10
Tue
Graduation Services Seminar @ 130 Koffolt Lab
Oct 10 @ 11:30 am – 12:30 pm

Speaker: Tim Watson, Director of Graduation Services

For graduate students approaching graduation: Come and learn about graduation requirements from the Graduate School.